Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997591 | 1.00 | GHSR (0.36) | GHSRGPR88CPB2BACE1SYK | |
| SCHEMBL8997715 | 0.89 | CPB2 (0.31) | GHSRGPR88CPB2 | |
| SCHEMBL8582293 | 0.88 | SYK (0.44) | GHSRSYK | |
| SCHEMBL8585491 | 0.84 | GHSR (0.42) | GHSRADRB2ADRB1ADRA1ARECQL | |
| SCHEMBL8612146 | 0.84 | GHSR (0.42) | GHSRKMT2AADRB2ADRB1ADRA1A | |
| SCHEMBL8581606 | 0.83 | GHSR (0.42) | GHSRADRB2ADRB1ADRA1ARECQL | |
| SCHEMBL8584100 | 0.80 | GHSR (0.42) | GHSRCPB2PCSK9ADRB2ADRB1 | |
| SCHEMBL8997886 | 0.79 | PRMT5 (0.31) | GHSR | |
| SCHEMBL8997612 | 0.77 | SYK (0.41) | SYKTSHR | |
| SCHEMBL8997761 | 0.76 | GHSR (0.33) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |