Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997619 | 0.92 | GHSR (0.35) | GHSRMTNR1AMTNR1BKCNH2ADRB2 | |
| SCHEMBL8997607 | 0.89 | GHSR (0.35) | GHSRMTNR1AMTNR1BKCNH2ADRB2 | |
| SCHEMBL8997626 | 0.88 | GHSR (0.35) | GHSRMTNR1AMTNR1BKCNH2ADRB2 | |
| SCHEMBL8997886 | 0.85 | PRMT5 (0.31) | GHSRPRMT5WDR77CASP1CASP3 | |
| SCHEMBL8585491 | 0.85 | GHSR (0.42) | GHSRMTNR1AMTNR1BKCNH2ADRB2 | |
| SCHEMBL8997625 | 0.83 | GHSR (0.37) | GHSRMTNR1AMTNR1BKCNH2ADRB2 | |
| SCHEMBL8997623 | 0.83 | GHSR (0.34) | GHSRKCNH2 | |
| SCHEMBL8559137 | 0.80 | GHSR (0.39) | GHSRMTNR1AMTNR1BHTR1A | |
| SCHEMBL8560312 | 0.80 | GHSR (0.39) | GHSRMTNR1AMTNR1BHTR1A | |
| SCHEMBL8997612 | 0.80 | SYK (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729972-A1 | Peptide derivatives of tetrahydronaphthalene | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-04 | — | — | EP | disclosed |