Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2018753 | 0.80 | TAAR1 (0.55) | HDAC1HDAC6KMT2AALDH1A1HPGD | |
| SCHEMBL2016545 | 0.78 | TAAR1 (0.59) | KMT2AALDH1A1ACHE | |
| SCHEMBL1745479 | 0.76 | ALOX5 (0.51) | CCR6HKDC1HDAC1HDAC6ALOX5 | |
| SCHEMBL3683771 | 0.74 | ALOX5 (0.46) | CCR6HKDC1HDAC1HDAC6ALOX5 | |
| SCHEMBL2097870 | 0.73 | NPY5R (0.56) | HDAC1HDAC6KMT2AALOX5 | |
| SCHEMBL8583957 | 0.73 | PTGS1 (0.40) | KMT2ACDK8CLK4CYP3A4ACHE | |
| SCHEMBL6942019 | 0.72 | HIF1A (0.53) | ALOX5IGF1RCYP3A4HIF1AHSD17B10 | |
| SCHEMBL30027871 | 0.72 | ALDH1A1 (0.66) | HDAC1HDAC6KMT2AHDAC3HDAC2 | |
| SCHEMBL1303490 | 0.72 | ALDH1A1 (0.66) | HDAC1HDAC6KMT2AHDAC3HDAC2 | |
| SCHEMBL11528973 | 0.72 | ALOX15 (0.54) | HDAC1HDAC6ALOX5IGF1RHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998037056-A1 | PHENOXYPROPANOLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM PLC (GB) | 1998-08-27 | — | — | WO | disclosed |