Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD5 | P21918 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | IAPP | P10997 | 3/20 | 0.49 |
| ▸ | YWHAG | P61981 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603208 | 0.83 | APP (0.50) | HIF1AHSD17B10CYP3A4CYP2D6DRD2 | |
| SCHEMBL6938226 | 0.79 | TRPV1 (0.49) | HIF1AHSD17B10CYP3A4CYP2D6DRD2 | |
| SCHEMBL13034052 | 0.78 | LTB4R (0.52) | HSD17B10ALDH1A1MAPTLMNAALOX5 | |
| SCHEMBL11172152 | 0.76 | NAMPT (0.45) | CYP3A4CYP2D6ALDH1A1MAPTLMNA | |
| SCHEMBL25132513 | 0.75 | ALOX15 (0.50) | HIF1AHSD17B10CYP3A4CYP2D6DRD2 | |
| SCHEMBL26491296 | 0.75 | HIF1A (0.51) | HIF1AHSD17B10CYP3A4CYP2D6DRD2 | |
| SCHEMBL30291871 | 0.75 | APP (0.73) | HIF1AHSD17B10KDM4EIAPPYWHAG | |
| SCHEMBL490911 | 0.75 | APP (0.73) | HIF1AHSD17B10KDM4EIAPPYWHAG | |
| SCHEMBL30364339 | 0.75 | HIF1A (0.50) | HIF1AHSD17B10CYP3A4CYP2D6DRD2 | |
| SCHEMBL67764 | 0.73 | HIF1A (0.65) | HIF1AHSD17B10CYP3A4CYP2D6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069307-A1 | 2-(3,4-Dihydroxyphenyl)ethyl-substituted carbonic acid derivatives and their use | HAARMANN & REIMER GMBH (DE) | 2003-04-10 | — | — | US | disclosed |
| EP-1284145-A1 | 2-(3,4-Dihydroxyphenyl)ethyl substituted carbonic acid derivatives and their use | HAARMANN & REIMER GMBH (DE) | 2003-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069307-A1 | 2-(3,4-Dihydroxyphenyl)ethyl-substituted carbonic acid derivatives and their use | NFE2L2, AGER, ME2 | HIF1A 126/4885HSD17B10 1254/4885CYP3A4 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.