Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28599111 | 0.98 | MEN1 (0.46) | MEN1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL8586307 | 0.80 | CES2 (0.52) | MEN1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL6200881 | 0.80 | MEN1 (0.44) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL10438873 | 0.80 | LMNA (0.61) | LMNAMAPTMAOBALDH1A1TSHR | |
| SCHEMBL156135 | 0.78 | HPGD (0.47) | MEN1KMT2ALMNAMAPTMAOB | |
| SCHEMBL7869484 | 0.78 | MAPT (0.61) | KMT2ALMNAMAPTRAB9ANPSR1 | |
| SCHEMBL3725791 | 0.78 | MAOB (0.43) | LMNAMAOBALDH1A1CES2CES1 | |
| SCHEMBL11300560 | 0.78 | LDHA (0.44) | MEN1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL9510016 | 0.78 | TDP1 (0.44) | LMNAMAPTRAB9AMAPK1ALDH1A1 | |
| SCHEMBL3364623 | 0.78 | LMNA (0.59) | LMNAMAPTMAOBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020009176-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | 田辺三菱製薬株式会社 | 2020-01-09 | — | — | WO | disclosed |