Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364349 | 0.91 | PARP1 (0.33) | AGTR2PDCD1CD274PARP1AGTR1 | |
| SCHEMBL8357510 | 0.91 | AGTR2 (0.37) | AGTR2PDCD1CD274POLBLMNA | |
| SCHEMBL8363436 | 0.88 | AGTR1 (0.37) | AGTR2AGTR1PPARGSMN1; SMN2 | |
| SCHEMBL8359678 | 0.87 | PPARG (0.39) | AGTR2AGTR1PPARG | |
| SCHEMBL8361975 | 0.85 | ALDH1A1 (0.36) | LMNAPPARGSMN1; SMN2 | |
| SCHEMBL8417421 | 0.85 | AGTR1 (0.34) | AGTR2PDCD1CD274AGTR1ABCB11 | |
| SCHEMBL8589024 | 0.84 | TP53 (0.35) | AGTR2POLBTP53PPARG | |
| SCHEMBL8357459 | 0.84 | AGTR2 (0.36) | AGTR2PDCD1CD274POLBLMNA | |
| SCHEMBL8359530 | 0.83 | AGTR1 (0.39) | AGTR2AGTR1ABCB11EGFRERBB2 | |
| SCHEMBL8359639 | 0.83 | PDCD1 (0.36) | AGTR2PDCD1CD274POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736555-A | HYPOTENSIVE AGENTS; FDA ORANGE BOOK LISTED PATENT FOR AZILSARTAN MEDOXOMIL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-07 | — | — | US | disclosed |