Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590131 | 0.85 | MCHR1 (0.53) | KDM4EALDH1A1HRH3SMN1; SMN2RXFP1 | |
| SCHEMBL8589733 | 0.84 | HRH3 (0.70) | RAB9AMAPTTDP1NPC1HRH3 | |
| SCHEMBL8711856 | 0.84 | MEN1 (0.53) | RAB9AKMT2AMEN1NPC1HTR1B | |
| SCHEMBL8590672 | 0.84 | KDR (0.45) | KMT2AKDM4EALDH1A1HRH3SMN1; SMN2 | |
| SCHEMBL8589516 | 0.84 | MEN1 (0.53) | RAB9AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8590451 | 0.83 | HRH3 (0.56) | RAB9AKDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL8589002 | 0.83 | ALDH1A1 (0.50) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL8589512 | 0.83 | ALDH1A1 (0.52) | RAB9AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8587699 | 0.82 | KDR (0.43) | KMT2AKDM4EALDH1A1HRH3SMN1; SMN2 | |
| SCHEMBL8590190 | 0.82 | KMT2A (0.47) | RAB9AKMT2AMEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |