Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590972 | 0.86 | UTS2R (0.44) | ALDH1A1LMNAKMT2AKDM4EMAPT | |
| SCHEMBL8591092 | 0.84 | KDR (0.39) | ALDH1A1LMNAKMT2AKDM4EPOLB | |
| SCHEMBL8711856 | 0.84 | MEN1 (0.53) | KMT2AMEN1HTR1BHDAC1 | |
| SCHEMBL8587717 | 0.83 | RAB9A (0.53) | ALDH1A1LMNAKMT2AKDM4EMAPT | |
| SCHEMBL8588968 | 0.82 | MCHR1 (0.41) | ALDH1A1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL8590131 | 0.77 | MCHR1 (0.53) | ALDH1A1KDM4E | |
| SCHEMBL8590571 | 0.77 | NLRP3 (0.46) | ALDH1A1LMNAKMT2AKDM4EMAPT | |
| SCHEMBL8709150 | 0.77 | KDR (0.47) | KMT2AMEN1POLBHTR1B | |
| SCHEMBL6541884 | 0.77 | MCHR1 (0.48) | ALDH1A1LMNAKMT2AKDM4EMAPT | |
| SCHEMBL8592685 | 0.74 | ALDH1A1 (0.47) | ALDH1A1LMNAKMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | claimed |
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |