Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11687320 | 0.91 | TSHR (0.44) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL8587749 | 0.86 | TSHR (0.46) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL11680205 | 0.84 | TSHR (0.50) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL8472802 | 0.81 | ALDH1A1 (0.43) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL65543 | 0.81 | TSHR (0.55) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL11679482 | 0.81 | LMNA (0.45) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL8975083 | 0.80 | TSHR (0.46) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL28805216 | 0.80 | TSHR (0.53) | TSHRTP53PDCD1CD274LMNA | |
| Benzoic Acid 1-Methylethyl Ester SCHEMBL31017505 | 0.79 | PDCD1 (0.75) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL11676196 | 0.79 | L3MBTL1 (0.43) | TSHRTP53PDCD1CD274LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671440-B1 | Monoazo dyes | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 1999-07-28 | — | — | EP | disclosed |
| US-5608042-A | DYEING POLYESTER ULTRAMICRO FIBERS | DYSTAR JAPAN LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5527888-A | USED FOR DYEING ULTRAMICRO POLYESTER FIBERS | DYSTAR JAPAN LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0671440-A2 | Monoazo dyes | DyStar Japan Ltd. (JP) | 1995-09-13 | — | — | EP | disclosed |