Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 8/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28126462 | 0.77 | CHRM5 (0.40) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL28486149 | 0.76 | CHRM5 (0.39) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL29179325 | 0.74 | CYP3A4 (0.42) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL28761585 | 0.73 | SCN1A (0.42) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL28235212 | 0.72 | LMNA (0.36) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL3084903 | 0.72 | — | — | |
| SCHEMBL10704506 | 0.71 | SCN1A (0.41) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL29050268 | 0.71 | SMN1; SMN2 (0.46) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL28223992 | 0.71 | CYP3A4 (0.39) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL3906050 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830432-A | Phospholipid drug derivatives | AMUR PHARMACUTICALS, INC. (US) | 1998-11-03 | — | — | US | disclosed |
| WO-1998043676-A1 | PHOSPHOLIPID DRUG DERIVATIVES | AMUR PHARMACEUTICALS, INC. (US) | 1998-10-08 | — | — | WO | disclosed |