Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 17/20 | 0.33 |
| ▸ | CASK | O14936 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.31 |
| ▸ | STK10 | O94804 | 1/20 | 0.31 |
| ▸ | CDK14 | O94921 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | MAK | P20794 | 1/20 | 0.31 |
| ▸ | CDK11B | P21127 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CLK3 | P49761 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591309 | 0.91 | NR1H4 (0.34) | NR1H4CASKROCK2CDKL5STK10 | |
| SCHEMBL8590976 | 0.88 | MEN1 (0.36) | NR1H4CASKROCK2CDKL5STK10 | |
| SCHEMBL8591321 | 0.82 | NR1H4 (0.32) | NR1H4 | |
| SCHEMBL8762848 | 0.80 | NR1H4 (0.35) | NR1H4 | |
| SCHEMBL8763742 | 0.80 | NR1H4 (0.36) | NR1H4 | |
| SCHEMBL6054846 | 0.80 | DHODH (0.35) | NR1H4CASKROCK2CDKL5STK10 | |
| SCHEMBL8822174 | 0.80 | SMURF2 (0.38) | NR1H4 | |
| SCHEMBL8762913 | 0.76 | SMURF2 (0.38) | NR1H4 | |
| SCHEMBL8763780 | 0.75 | BCAT2 (0.39) | — | |
| SCHEMBL8762928 | 0.74 | SMURF2 (0.36) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998051153-A1 | HERBICIDAL METHODS AND DERIVATIVES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-11-19 | — | — | WO | disclosed |