Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588451 | 0.81 | SMN1; SMN2 (0.54) | ALDH1A1MAPTLMNAGAAHPGD | |
| SCHEMBL10192812 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAHPGDHSD17B10 | |
| SCHEMBL5167640 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAGAAHPGD | |
| SCHEMBL3522023 | 0.69 | MAPT (0.55) | ALDH1A1MAPTLMNAGAAHPGD | |
| SCHEMBL28178057 | 0.69 | ALDH1A1 (0.59) | ALDH1A1GAAL3MBTL1ATMTDP1 | |
| SCHEMBL2905392 | 0.68 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAGAAHPGD | |
| Benzophenone SCHEMBL27766299 | 0.68 | ALDH1A1 (0.82) | ALDH1A1MAPTLMNAHPGDPBRM1 | |
| SCHEMBL2897987 | 0.67 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAGAAHPGD | |
| SCHEMBL14445502 | 0.66 | HPD (0.56) | ALDH1A1MAPTLMNAHSD17B10HTT | |
| SCHEMBL17372132 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249813-B1 | CERTAIN SUBSTITUTED 3-AMINO-2-BENZOYLCYCLOHEX-2-ENONES | STAUFFER CHEMICAL COMPANY (US) | 1991-07-24 | — | — | EP | claimed |
| US-4775411-A | HERBICIDES | STAUFFER CHEMICA COMPANY (US) | 1988-10-04 | — | — | US | claimed |
| EP-0249813-A1 | Certain substituted 3-amino-2-benzoylcyclohex-2-enones | STAUFFER CHEMICAL COMPANY (US) | 1987-12-23 | — | — | EP | claimed |
| US-7670991-B2 | Substituted benzoylcyclohexenones and their use as herbicidal agents | BAYER CROPSCIENCE AG (DE) | 2010-03-02 | — | — | US | disclosed |
| US-20040171491-A1 | Substituted benzoylcyclohexenones and their use as herbicidal agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-09-02 | — | — | US | disclosed |
| EP-0249813-B1 | CERTAIN SUBSTITUTED 3-AMINO-2-BENZOYLCYCLOHEX-2-ENONES | STAUFFER CHEMICAL COMPANY (US) | 1991-07-24 | — | — | EP | disclosed |
| EP-0249813-B1 | CERTAIN SUBSTITUTED 3-AMINO-2-BENZOYLCYCLOHEX-2-ENONES | STAUFFER CHEMICAL COMPANY (US) | 1991-07-24 | — | — | EP | disclosed |
| US-4775411-A | HERBICIDES | STAUFFER CHEMICA COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
| US-4775411-A | HERBICIDES | STAUFFER CHEMICA COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
| EP-0249813-A1 | Certain substituted 3-amino-2-benzoylcyclohex-2-enones | STAUFFER CHEMICAL COMPANY (US) | 1987-12-23 | — | — | EP | disclosed |
| EP-0249813-A1 | Certain substituted 3-amino-2-benzoylcyclohex-2-enones | STAUFFER CHEMICAL COMPANY (US) | 1987-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171491-A1 | Substituted benzoylcyclohexenones and their use as herbicidal agents | DDT, CYP1B1, CYP1A1 | ALDH1A1 291/4885MAPT 4728/4885LMNA 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.