Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 5/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590131 | 0.88 | MCHR1 (0.53) | SMN1; SMN2KDRHRH3MCHR1KIT | |
| SCHEMBL8589432 | 0.86 | ALDH1A1 (0.51) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL8612301 | 0.84 | THRB (0.52) | HRH3TP53RXFP1LMNA | |
| SCHEMBL8617355 | 0.84 | MAPT (0.52) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL8589629 | 0.81 | HRH3 (0.50) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL8589733 | 0.81 | HRH3 (0.70) | MAPTRAB9ANPC1KDRHRH3 | |
| SCHEMBL8587504 | 0.80 | HRH3 (0.53) | HRH3MCHR1 | |
| SCHEMBL8587717 | 0.80 | RAB9A (0.53) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL8589516 | 0.80 | MEN1 (0.53) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL8617490 | 0.80 | HRH3 (0.49) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |