Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1345174 | 0.93 | LTB4R (0.46) | LTB4RLTB4R2PTGS1PTGS2MAPT | |
| SCHEMBL8590234 | 0.84 | PTGS1 (0.51) | LTB4RLTB4R2PTGS1PTGS2MT-CO2 | |
| SCHEMBL14121701 | 0.80 | HRH3 (0.42) | LTB4RLTB4R2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL28780509 | 0.80 | LTB4R (0.43) | LTB4RLTB4R2PTGS1PTGS2MAPT | |
| SCHEMBL3674499 | 0.79 | PTGS2 (0.69) | LTB4RLTB4R2PTGS1PTGS2MAPT | |
| SCHEMBL9425565 | 0.79 | PTGS2 (0.56) | LTB4RLTB4R2PTGS1PTGS2MAPT | |
| SCHEMBL10276277 | 0.78 | PTGS2 (0.54) | LTB4RLTB4R2PTGS1PTGS2MAPT | |
| SCHEMBL66534 | 0.78 | PTGS2 (0.64) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL2319534 | 0.78 | PTGS2 (0.58) | LTB4RLTB4R2PTGS1PTGS2MAPT | |
| SCHEMBL1345158 | 0.78 | PTGS2 (0.64) | PTGS1PTGS2MAPTCXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998057910-A2 | CYCLOOXYGENASE-I SELECTIVE INHIBITORS AND THE USE THEREOF AS ANALGESIC, ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | LABORATORIOS MENARINI S.A. (ES) | 1998-12-23 | — | — | WO | claimed |