Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.64 |
| ▸ | MME | P08473 | 5/20 | 0.48 |
| ▸ | ACE | P12821 | 3/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GCGR | P47871 | 1/20 | 0.45 |
| ▸ | GIPR | P48546 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TRHDE | Q9UKU6 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592530 | 1.00 | PIN1 (0.64) | PIN1MMEACECPA1ACE2 | |
| SCHEMBL8589911 | 0.82 | SMN1; SMN2 (0.54) | MEN1KMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL8590389 | 0.81 | SMN1; SMN2 (0.53) | PIN1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL8590055 | 0.79 | MAPT (0.63) | PIN1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL27706437 | 0.75 | SMN1; SMN2 (0.63) | MEN1KMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL8591001 | 0.74 | CACNA1G (0.55) | PIN1MMEACECPA1ACE2 | |
| SCHEMBL8591003 | 0.74 | CACNA1G (0.55) | PIN1MMEACECPA1ACE2 | |
| SCHEMBL28978182 | 0.73 | SMN1; SMN2 (0.51) | PIN1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL28978186 | 0.73 | SMN1; SMN2 (0.51) | PIN1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL8592529 | 0.73 | GCGR (0.40) | PIN1MMEMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744493-A | POSSESS ACTIVITY WITH RESPECT TO THE CENTRAL NERVOUS SYSTEM, THE CARDIOVASCULAR SYSTEM AND THE GASTROINTESTINAL SYSTEM | SANOFI (FR) | 1998-04-28 | — | — | US | disclosed |
| US-5744491-A | POSSESS ACTIVITY WITH RESPECT TO THE CENTRAL NERVOUS SYSTEM, THE CARDIOVASCULAR SYSTEM AND THE GASTROINTESTINAL SYSTEM | SANOFI (FR) | 1998-04-28 | — | — | US | disclosed |
| US-5635526-A | POSSESSES ACTIVITY WITH RESPECT TO THE CENTRAL NERVOUS SYSTEM, THE CARDIOVASCULAR SYSTEM OR THE GASTROINTESTINAL SYSTEM | SANOFI (FR) | 1997-06-03 | — | — | US | disclosed |
| US-5616592-A | USEFUL FOR DISORDERS OF CARDIOVASCULAR, GASTROINTESTINAL AND PSYCHOLOGICAL DISORDERS | SANOFI (FR) | 1997-04-01 | — | — | US | disclosed |
| US-5607958-A | NEUROTENSIN RECEPTOR BINDERS | SANOFI (FR) | 1997-03-04 | — | — | US | disclosed |
| US-5420141-A | Capable of binding to neurotensin receptor | SANOFI (FR) | 1995-05-30 | — | — | US | disclosed |