Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250148 | 0.92 | TOP2A (0.53) | TOP2ANPC1RAB9AALDH1A1HPGD | |
| SCHEMBL5335888 | 0.92 | TOP2A (0.53) | TOP2ANPC1RAB9AALDH1A1HPGD | |
| SCHEMBL22687002 | 0.92 | TOP2A (0.53) | TOP2ANPC1RAB9AALDH1A1HPGD | |
| SCHEMBL285170 | 0.85 | ALDH1A1 (0.48) | SNCATOP2ANPC1RAB9AALDH1A1 | |
| SCHEMBL28887970 | 0.85 | ALDH1A1 (0.48) | SNCATOP2ANPC1RAB9AALDH1A1 | |
| SCHEMBL285168 | 0.85 | ALDH1A1 (0.48) | SNCATOP2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7567677 | 0.85 | PTGS2 (0.50) | TOP2ANPC1RAB9AALDH1A1HPGD | |
| SCHEMBL6421503 | 0.82 | SNCA (0.64) | SNCAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6421501 | 0.82 | SNCA (0.64) | SNCAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6688214 | 0.80 | MEN1 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000231-A9 | HIGH-THROUGHPUT SCREENING ASSAY SYSTEMS IN MICROSCALE FLUIDIC DEVICES | — | 1998-04-23 | — | — | WO | disclosed |