SCHEMBL85937

SCHEMBL85937

C=CC(=O)Oc1ccc2c(=O)c3c(ccc4ccccc43)oc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.45
MAOA P21397 2/20 0.45
RAB9A P51151 2/20 0.45
ABCG2 Q9UNQ0 9/20 0.45
MAPT P10636 4/20 0.43
ALDH1A1 P00352 3/20 0.43
KMT2A Q03164 3/20 0.43
PPARG P37231 1/20 0.43
NCOA2 Q15596 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
KDM4E B2RXH2 2/20 0.42
PAX8 Q06710 2/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1A2 P05177 1/20 0.41
FYN P06241 1/20 0.41
MAPK3 P27361 1/20 0.41
AHR P35869 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20346592 0.86 KDM4E (0.57) NPC1MAOARAB9AABCG2MAPT
SCHEMBL20346581 0.81 MAOA (0.69) NPC1MAOARAB9AABCG2MAPT
SCHEMBL20346588 0.78 CA12 (0.52) NPC1MAOARAB9AABCG2MAPT
SCHEMBL8836311 0.77 LMNA (0.44) NPC1MAOARAB9AMAPTALDH1A1
SCHEMBL6549480 0.77 MAOA (0.46) NPC1MAOARAB9AMAPTALDH1A1
SCHEMBL15292034 0.77 ALDH1A1 (0.47) MAPTALDH1A1KMT2AKDM4ETDP1
SCHEMBL85949 0.77 KDM4E (0.62) NPC1MAOARAB9AABCG2MAPT
SCHEMBL20346579 0.76 MAOA (0.67) NPC1MAOARAB9AABCG2MAPT
SCHEMBL86424 0.76 MAPT (0.45) NPC1MAOARAB9AABCG2MAPT
SCHEMBL20346641 0.74 TTR (0.49) NPC1MAOARAB9AABCG2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053095-B1 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
EP-2053095-A2 Ink composition and inkjet recording method using the same Fujifilm Corporation (JP) 2009-04-29 EP disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 NPC1 4271/4885MAOA 415/4885RAB9A 974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.