Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567818 | 0.85 | PTGS2 (0.34) | ALDH1A1KDM4EMAPTALOX15TSHR | |
| SCHEMBL9278686 | 0.85 | IKBKB (0.36) | ALDH1A1KDM4EMAPTALOX15TSHR | |
| SCHEMBL8463065 | 0.78 | PTGS2 (0.56) | ALDH1A1KDM4EMAPTTSHRNPSR1 | |
| SCHEMBL353410 | 0.76 | — | — | |
| SCHEMBL4327521 | 0.76 | — | — | |
| SCHEMBL161729 | 0.76 | — | — | |
| SCHEMBL933947 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTTSHRHPGD | |
| SCHEMBL8957137 | 0.76 | KDM4E (0.46) | ALDH1A1KDM4EMAPTALOX15TSHR | |
| SCHEMBL2696901 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTTSHRL3MBTL1 | |
| SCHEMBL27654721 | 0.74 | PTGS2 (0.43) | ALDH1A1KDM4EMAPTPTGS2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562382-B1 | Process for the preparation of isoxazole-3,4-dicarboxylic acid derivatives | BASF AG (DE) | 1998-01-21 | — | — | EP | claimed |
| EP-0562377-B1 | Preparation of isoxazole-3-carboxamide-4-carboxylic acid esters by selective amidation | BASF AG (DE) | 1997-05-14 | — | — | EP | claimed |
| US-5276160-A | Amidation of primary or secondary amines | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | claimed |
| US-5264580-A | Reaction of hydroximyl chlorides and beta-keto acids or esters, cyclization | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-23 | — | — | US | claimed |
| JP-6016650-A | — | — | None | — | — | JP | disclosed |
| CN-115232085-B | Malonate compound, preparation method and application thereof | 贵州工业职业技术学院 | 2023-09-05 | — | — | CN | disclosed |
| CN-115232085-A | Malonate type compound, preparation method and application thereof | 贵州理工学院 | 2022-10-25 | — | — | CN | disclosed |
| CN-105875625-A | Method for producing novel rimsulfuron formulations and use thereof | 龙灯农业化工国际有限公司 | 2016-08-24 | — | — | CN | disclosed |
| EP-0562382-B1 | Process for the preparation of isoxazole-3,4-dicarboxylic acid derivatives | BASF AG (DE) | 1998-01-21 | — | — | EP | disclosed |
| US-5576270-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-19 | — | — | US | disclosed |
| JP-H0616650-A | PRODUCTION OF 3-CARBAMOYLISOXAZOLE-4-CARBOXYLIC ESTER | BASF AG | 1994-01-25 | — | — | JP | disclosed |
| US-5276160-A | Amidation of primary or secondary amines | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
| US-4137237-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4093622-A | Pyridine esters of cyclopropane-carboxylic acid | ZOECON CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4070475-A | THIOALKYL-, AMINOALKYL-, AND OXYALKYL- SUBSTITUTED GUANIDINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-01-24 | — | — | US | disclosed |
| US-4024271-A | INHIBITORS OF HISTAMINE ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-17 | — | — | US | disclosed |
| US-4022797-A | PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-10 | — | — | US | disclosed |
| US-4018931-A | INHIBITION OF H-2 HISTAMINE RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-04-19 | — | — | US | disclosed |
| US-3950333-A | HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |
| US-3950353-A | HISTAMINE INHIBITORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |