Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2696901 | 0.87 | ALDH1A1 (0.44) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL158855 | 0.79 | POLB (0.40) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL8957108 | 0.78 | DPP4 (0.34) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL8595148 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2TSHR | |
| SCHEMBL8308653 | 0.73 | RIPK1 (0.34) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL8957126 | 0.69 | NPC1 (0.42) | ALDH1A1KDM4EPOLBAPEX1TSHR | |
| SCHEMBL8305864 | 0.69 | KDM4E (0.33) | ALDH1A1KDM4EGAAHPGDSMN1; SMN2 | |
| SCHEMBL20483743 | 0.68 | ACE2 (0.30) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL9284100 | 0.68 | KDM4E (0.51) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL8957137 | 0.67 | KDM4E (0.46) | ALDH1A1KDM4EGAAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451808-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011003793-A1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2011-01-13 | — | — | WO | disclosed |