Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479423 | 0.81 | ADRB3 (0.53) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL6949036 | 0.81 | MEN1 (0.53) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8479504 | 0.80 | CYP11B2 (0.44) | CYP11B2ALDH1A1NAMPTKDM4EPKM | |
| SCHEMBL8477891 | 0.80 | MEN1 (0.55) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8079406 | 0.80 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4EADRB1 | |
| SCHEMBL7772042 | 0.80 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4EADRB1 | |
| SCHEMBL8477434 | 0.80 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4EADRB1 | |
| SCHEMBL8479493 | 0.79 | MAPK1 (0.54) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8481421 | 0.79 | MEN1 (0.52) | CYP11B2MEN1KMT2AALDH1A1KDM1A | |
| SCHEMBL8477371 | 0.79 | CYP19A1 (0.50) | CYP11B2MEN1KMT2AALDH1A1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |