Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.37 |
| ▸ | ARNT | P27540 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314556 | 0.77 | — | — | |
| SCHEMBL2469875 | 0.76 | ALDH1A1 (0.49) | ATMTDP1MAPTALDH1A1HTT | |
| SCHEMBL27823034 | 0.74 | ATM (0.42) | ATMTDP1MAPTALDH1A1HTT | |
| SCHEMBL11669404 | 0.71 | S100A4 (0.37) | MAPTMEN1KMT2A | |
| SCHEMBL3712468 | 0.71 | ALDH3A1 (0.47) | SOS1ATMTDP1MAPTALDH1A1 | |
| SCHEMBL10800614 | 0.71 | GAA (0.39) | ATMTDP1MAPTALDH1A1HTT | |
| SCHEMBL562935 | 0.68 | S1PR2 (0.47) | MAPTALDH1A1 | |
| SCHEMBL12877829 | 0.68 | ALDH1A1 (0.40) | TDP1MAPTALDH1A1HTTKMT2A | |
| SCHEMBL2567841 | 0.68 | HTR6 (0.33) | — | |
| SCHEMBL18956811 | 0.67 | MAPT (0.51) | SOS1EPAS1ARNTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673370-B1 | TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS | UPJOHN CO (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5523403-A | Tropone-substituted phenyloxazolidinone antibacterial agents | THE UPJOHN COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| EP-0673370-A1 | TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013649-A1 | TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS | THE UPJOHN COMPANY (US) | 1994-06-23 | — | — | WO | disclosed |