Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592698 | 0.83 | HTR1A (0.57) | LMNAALDH1A1TSHRNPSR1MEN1 | |
| SCHEMBL8592481 | 0.76 | LMNA (0.47) | LMNAHTTALDH1A1TSHRNPSR1 | |
| SCHEMBL9527755 | 0.76 | ALDH1A1 (0.57) | LMNAHTTALDH1A1TSHRNPSR1 | |
| SCHEMBL7768608 | 0.75 | MAPT (0.60) | LMNAHTTALDH1A1TSHRNPSR1 | |
| SCHEMBL28226906 | 0.75 | ALDH1A1 (0.77) | LMNAHTTALDH1A1TSHRNPSR1 | |
| SCHEMBL631027 | 0.74 | LMNA (0.70) | LMNAHTTALDH1A1TSHRNPSR1 | |
| SCHEMBL8596199 | 0.74 | NOTUM (0.51) | LMNAHTTALDH1A1TSHRNPSR1 | |
| SCHEMBL8592712 | 0.74 | CHIA (0.47) | LMNAHTTALDH1A1L3MBTL1MEN1 | |
| SCHEMBL31642340 | 0.73 | L3MBTL1 (0.61) | LMNAHTTALDH1A1TSHRNPSR1 | |
| SCHEMBL31642133 | 0.73 | L3MBTL1 (0.61) | LMNAHTTALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815870-A2 | Composition for prohylaxis or treatment of cerebral infarction | Takeda Chemical Industries, Ltd. (JP) | 1998-01-07 | — | — | EP | disclosed |