Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567843 | 0.85 | POLB (0.43) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL8627624 | 0.82 | MAPT (0.39) | MAPTALDH1A1LMNAGAANPC1 | |
| SCHEMBL8597779 | 0.82 | ESR1 (0.48) | MAPTALDH1A1LMNAGAANPC1 | |
| SCHEMBL8599650 | 0.81 | CYP1A2 (0.51) | MAPTALDH1A1LMNAGAAPOLB | |
| SCHEMBL8597821 | 0.80 | LMNA (0.43) | MAPTALDH1A1LMNAGAACYP1A2 | |
| SCHEMBL8601694 | 0.78 | ALDH1A1 (0.42) | MAPTALDH1A1LMNAGAANPC1 | |
| SCHEMBL8596001 | 0.78 | SMN1; SMN2 (0.49) | MAPTALDH1A1LMNAGAAHTT | |
| SCHEMBL8563611 | 0.78 | PIN1 (0.54) | LMNANPC1RAB9AHTTPOLB | |
| SCHEMBL12665019 | 0.78 | MAPT (0.41) | MAPTALDH1A1LMNAGAANPC1 | |
| SCHEMBL9602005 | 0.77 | SMN1; SMN2 (0.51) | MAPTALDH1A1LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |