Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10332242 | 0.85 | POLB (0.44) | ALDH1A1MAPTCYP1A2POLBHTT | |
| SCHEMBL8599650 | 0.78 | CYP1A2 (0.51) | ALDH1A1MAPTLMNAGAACYP1A2 | |
| SCHEMBL8565327 | 0.78 | MEN1 (0.52) | ALDH1A1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL8596247 | 0.78 | MAPT (0.44) | ALDH1A1MAPTLMNAGAACYP1A2 | |
| SCHEMBL8599760 | 0.77 | POLB (0.41) | ALDH1A1MAPTLMNAGAACYP1A2 | |
| SCHEMBL8598392 | 0.76 | POLB (0.43) | ALDH1A1MAPTLMNAGAACYP1A2 | |
| SCHEMBL8597355 | 0.76 | TLR8 (0.44) | ALDH1A1MAPTLMNAGAACYP1A2 | |
| SCHEMBL8596001 | 0.75 | SMN1; SMN2 (0.49) | ALDH1A1MAPTLMNAGAAHTT | |
| SCHEMBL8598414 | 0.75 | MAPT (0.47) | ALDH1A1MAPTLMNAGAACYP1A2 | |
| SCHEMBL8599819 | 0.74 | PLA2G2A (0.44) | ALDH1A1MAPTLMNAGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |