SCHEMBL8596305

SCHEMBL8596305

CCCCCNS(=O)(=O)c1cc([N+](=O)[O-])nc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.47
CA9 Q16790 2/20 0.47
RECQL P46063 1/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2C19 P33261 2/20 0.46
MEN1 O00255 1/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
NPY5R Q15761 6/20 0.41
AGTR1 P30556 1/20 0.41
AGTR2 P50052 1/20 0.41
POLB P06746 2/20 0.40
ELANE P08246 2/20 0.40
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8598916 0.82 TXNRD1 (0.44) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL8562398 0.81 CYP19A1 (0.51) CA12CA9NPY5RALDH1A1KDM4E
SCHEMBL8625854 0.81 CA2 (0.42) CYP1A2CYP3A4CYP2C19MEN1TSHR
SCHEMBL8598728 0.80 ALDH1A1 (0.43) CA12CA9RECQLCYP1A2CYP3A4
SCHEMBL8597034 0.79 KDM4E (0.42) CA12CYP1A2MEN1TSHRKMT2A
SCHEMBL8598313 0.79 SLC2A1 (0.49) CYP2C19ELANELMNAMAPTMAPK1
SCHEMBL8596066 0.76 NPY5R (0.43) CA12CA9RECQLCYP1A2CYP3A4
SCHEMBL27542356 0.76 ALDH1A1 (0.42) MEN1KMT2APOLBALDH1A1KDM4E
SCHEMBL8564388 0.76 ALDH1A1 (0.48) CYP1A2CYP3A4CYP2C19MEN1TSHR
SCHEMBL8600292 0.76 CA12 (0.40) CA12CA9RECQLCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735025-B1 Process for producing aminonitropyridines SUMITOMO CHEMICAL CO (JP) 1998-07-01 EP disclosed
US-5648496-A AMINATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-15 US disclosed
EP-0735025-A1 Process for producing aminonitropyridines SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed