Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 2/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743876 | 1.00 | ADORA2A (0.46) | ADORA2AADORA3ADORA2BADORA1TP53 | |
| Benzene SCHEMBL27650186 | 0.87 | PI4KA (0.48) | ADORA2AADORA3ADORA2BADORA1PI4KA | |
| SCHEMBL13269091 | 0.87 | PI4KA (0.45) | ADORA2AADORA3ADORA2BADORA1PI4KA | |
| SCHEMBL5525776 | 0.87 | PI4KA (0.45) | ADORA2AADORA3ADORA2BADORA1PI4KA | |
| SCHEMBL13268818 | 0.87 | PI4KA (0.45) | ADORA2AADORA3ADORA2BADORA1PI4KA | |
| SCHEMBL6829143 | 0.86 | PI4KA (0.48) | ADORA2AADORA3ADORA2BADORA1HIF1A | |
| SCHEMBL29721329 | 0.85 | ADORA3 (0.50) | ADORA2AADORA3ADORA2BADORA1PI4KA | |
| SCHEMBL7435441 | 0.85 | ADORA3 (0.50) | ADORA2AADORA3ADORA2BADORA1PI4KA | |
| SCHEMBL10710442 | 0.85 | ADORA3 (0.46) | ADORA2AADORA3ADORA2BADORA1PI4KA | |
| SCHEMBL2270700 | 0.84 | ADORA2A (0.51) | ADORA2AADORA3ADORA2BADORA1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189255-A1 | DRUG-ELUTING STENTS FOR ADENOSINE RECEPTOR MODULATION | PURDUE RESEARCH FOUNDATION | 2011-08-04 | — | — | US | claimed |
| EP-0735888-B1 | PURINE COMPOSITIONS | FUKUNAGA ATSUO F (US) | 2005-06-29 | — | — | EP | claimed |
| US-5070877-A | Using adenosin receptor agonist | MEDCO RESEARCH, INC. (US) | 1991-12-10 | — | — | US | claimed |
| EP-0181129-B1 | N6-SUBSTITUTED DEOXYRIBOSE ANALOGS OF ADENOSINES | WARNER-LAMBERT COMPANY (US) | 1989-03-08 | — | — | EP | claimed |
| EP-0181129-A2 | N6-substituted deoxyribose analogs of adenosines | WARNER-LAMBERT COMPANY (US) | 1986-05-14 | — | — | EP | claimed |
| JP-4124143-A | — | — | None | — | — | JP | disclosed |
| US-9414901-B2 | Drug-eluting stents for adenosine receptor modulation | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-08-16 | — | — | US | disclosed |
| WO-2012068539-A1 | USE AND COMPOSITION OF QUERCETIN-3'-O-SULFATE FOR THERAPEUTIC TREATMENT | LIMERICK BIOPHARMA, INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| EP-1718757-B1 | GLIMEPIRIDE- AND INSULIN-INDUCED GLYCOSYLPHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C REGULATION | SANOFI AVENTIS DEUTSCHLAND (DE) | 2012-03-28 | — | — | EP | disclosed |
| US-8017350-B2 | Glimepiride- and insulin-induced glycosylphosphatidylinositol-specific phospholipase C regulation | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-09-13 | — | — | US | disclosed |
| US-20110189255-A1 | DRUG-ELUTING STENTS FOR ADENOSINE RECEPTOR MODULATION | PURDUE RESEARCH FOUNDATION | 2011-08-04 | — | — | US | disclosed |
| US-7964731-B2 | Isotopically marked quinoline derivatives as adenosin A3 receptor ligands | SANOFI-AVENTIS (FR) | 2011-06-21 | — | — | US | disclosed |
| WO-1996038728-A1 | A METHOD FOR MEASURING THE A2a RECEPTOR BINDING ACTIVITY OF COMPOUNDS OF PHARMACOLOGICAL INTEREST BY THE USE OF THE TRITIATED LIGAND (3H)-SCH 58261 | SCHERING-PLOUGH S.P.A. (IT) | 1996-12-05 | — | — | WO | disclosed |
| EP-0501379-A2 | Xanthine compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| JP-H04124143-A | CARDIAC INFARCTION MEDICINE CONTAINING ADENOSINE OR ITS RELATED COMPOUND AS ACTIVE INGREDIENT | MEDCO RES INC | 1992-04-24 | — | — | JP | disclosed |
| US-5070877-A | Using adenosin receptor agonist | MEDCO RESEARCH, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| US-5070877-A | Using adenosin receptor agonist | MEDCO RESEARCH, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0354638-A2 | Use of adenosine and its derivatives in diagnosis | MEDCO RESEARCH INC (US) | 1990-02-14 | — | — | EP | disclosed |
| EP-0181129-B1 | N6-SUBSTITUTED DEOXYRIBOSE ANALOGS OF ADENOSINES | WARNER-LAMBERT COMPANY (US) | 1989-03-08 | — | — | EP | disclosed |
| EP-0181129-A2 | N6-substituted deoxyribose analogs of adenosines | WARNER-LAMBERT COMPANY (US) | 1986-05-14 | — | — | EP | disclosed |