Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | NR1D1 | P20393 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601277 | 0.88 | DCTPP1 (0.41) | DCTPP1ALDH1A1KDM4EKMT2ACXCR3 | |
| SCHEMBL8602012 | 0.84 | DCTPP1 (0.42) | DCTPP1ALDH1A1KDM4EPKN1PKN2 | |
| SCHEMBL1885760 | 0.82 | DCTPP1 (0.42) | DCTPP1ALDH1A1KDM4E | |
| SCHEMBL8600616 | 0.78 | DCTPP1 (0.36) | DCTPP1ALDH1A1KDM4EADORA3KMT2A | |
| SCHEMBL261021 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AHTTMEN1 | |
| SCHEMBL2054568 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AHTTMEN1 | |
| SCHEMBL261338 | 0.73 | ALDH1A1 (0.44) | ALDH1A1KDM4EADORA3HTTMAPT | |
| SCHEMBL3730551 | 0.72 | DCTPP1 (0.57) | DCTPP1ALDH1A1KDM4EKMT2AHTT | |
| SCHEMBL7484481 | 0.71 | DCTPP1 (0.47) | DCTPP1ALDH1A1HTTMAPT | |
| SCHEMBL1885547 | 0.69 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |