Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598596 | 0.84 | DCTPP1 (0.43) | DCTPP1ALDH1A1KDM4EKMT2ANR1D1 | |
| SCHEMBL8599561 | 0.83 | KDM4E (0.44) | ALDH1A1KDM4EKMT2AMAPTPKN1 | |
| SCHEMBL1885760 | 0.81 | DCTPP1 (0.42) | DCTPP1ALDH1A1KDM4EPABPC1IRAK1 | |
| SCHEMBL8601277 | 0.80 | DCTPP1 (0.41) | DCTPP1ALDH1A1KDM4EKMT2AHTT | |
| SCHEMBL8599822 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4EKMT2AHTTMAPT | |
| SCHEMBL261338 | 0.72 | ALDH1A1 (0.44) | ALDH1A1KDM4EHTTMAPTNPSR1 | |
| SCHEMBL3730551 | 0.71 | DCTPP1 (0.57) | DCTPP1ALDH1A1KDM4EKMT2AHTT | |
| SCHEMBL261021 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AHTTLMNA | |
| SCHEMBL2054568 | 0.70 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AHTTLMNA | |
| SCHEMBL27703390 | 0.70 | ALDH1A1 (0.41) | ALDH1A1KDM4EKMT2ANR1D1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |