Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598596 | 0.78 | DCTPP1 (0.43) | DCTPP1HTTADORA3ADORA2AALDH1A1 | |
| SCHEMBL8601277 | 0.72 | DCTPP1 (0.41) | DCTPP1HTTALDH1A1KDM4EKMT2A | |
| SCHEMBL7484481 | 0.70 | DCTPP1 (0.47) | DCTPP1HTTALDH1A1MAPTMET | |
| SCHEMBL2860553 | 0.67 | MET (0.40) | DCTPP1HTTALDH1A1MAPTKDM4E | |
| SCHEMBL14423542 | 0.67 | ELANE (0.41) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28461199 | 0.65 | PABPC1 (0.45) | DCTPP1HTTALDH1A1MAPTMEN1 | |
| SCHEMBL29750672 | 0.65 | MAPT (0.35) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8602012 | 0.65 | DCTPP1 (0.42) | DCTPP1HTTADORA3ALDH1A1MAPT | |
| SCHEMBL1885760 | 0.65 | DCTPP1 (0.42) | DCTPP1ALDH1A1KDM4E | |
| SCHEMBL16811748 | 0.64 | ALDH1A1 (0.56) | HTTALDH1A1MAPTTDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |