Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 5/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.38 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598543 | 0.91 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DPTGES | |
| SCHEMBL8600336 | 0.85 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DPTGES | |
| SCHEMBL8595606 | 0.84 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DPTGES | |
| SCHEMBL8598600 | 0.84 | THRB (0.42) | PDE4BPDE4APDE4CPDE4DPTGES | |
| SCHEMBL8602102 | 0.84 | TYK2 (0.44) | PDE4BPDE4APDE4CPDE4DP2RX1 | |
| SCHEMBL8600059 | 0.83 | PTGES (0.40) | PDE4BPDE4APDE4CPDE4DPTGES | |
| SCHEMBL8597865 | 0.82 | PDE4A (0.39) | PDE4BPDE4APDE4CPDE4DPTGES | |
| SCHEMBL8596934 | 0.81 | CNR1 (0.40) | PDE4BPDE4APDE4CPDE4DPTGES | |
| SCHEMBL8601221 | 0.81 | HPGD (0.46) | PDE4BPDE4APDE4CPDE4DPTGES | |
| SCHEMBL8599983 | 0.81 | TYK2 (0.40) | PTGESLCKTYK2DCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |