Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 4/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602720 | 0.87 | PDE4B (0.44) | DCTPP1PDE4BPDE4APDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL8599164 | 0.85 | ALDH1A1 (0.40) | DCTPP1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8598543 | 0.85 | PDE4B (0.43) | TYK2DCTPP1PDE4BPDE4APDE4C | |
| SCHEMBL8598985 | 0.84 | PDE4B (0.42) | TYK2DCTPP1PDE4BPDE4APDE4C | |
| SCHEMBL8597750 | 0.83 | DCTPP1 (0.48) | DCTPP1PIK3C2BBRD4CREBBP | |
| SCHEMBL8595606 | 0.83 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DPIK3C2B | |
| SCHEMBL8602351 | 0.82 | TYK2 (0.48) | TYK2DCTPP1JAK2KDRBRD4 | |
| SCHEMBL8600336 | 0.80 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DPIK3C2B | |
| SCHEMBL8601221 | 0.80 | HPGD (0.46) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8600059 | 0.79 | PTGES (0.40) | PDE4BPDE4APDE4CPDE4DPIK3C2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |