Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | MGMT | P16455 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572912 | 0.84 | MGMT (0.39) | MAPTMGMTLMNAMEN1KMT2A | |
| SCHEMBL8598969 | 0.79 | ALDH1A1 (0.46) | MAPTNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL8626136 | 0.79 | CYP19A1 (0.38) | MAPTNPC1RAB9ANCOA1NCOA3 | |
| SCHEMBL1959760 | 0.79 | MEN1 (0.45) | MAPTMGMTLMNAMEN1KMT2A | |
| SCHEMBL30622686 | 0.79 | MEN1 (0.45) | MAPTMGMTLMNAMEN1KMT2A | |
| SCHEMBL8597378 | 0.78 | MEN1 (0.41) | MAPTMGMTNPC1RAB9ACYP19A1 | |
| SCHEMBL9965037 | 0.78 | MAPT (0.42) | CNR1ACHECNR2MAPTMGMT | |
| SCHEMBL5333048 | 0.78 | CYP3A4 (0.40) | CNR1ACHECNR2NPC1LMNA | |
| SCHEMBL28203110 | 0.77 | MEN1 (0.40) | MAPTMGMTRAB9ACYP19A1LMNA | |
| SCHEMBL8599059 | 0.77 | CYP19A1 (0.43) | MAPTNPC1RAB9ACYP19A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |