SCHEMBL8599101

SCHEMBL8599101

CCOC(=O)C(F)(F)C(F)CO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP4F2 P78329 3/20 0.38
CYP4A11 Q02928 3/20 0.38
MMP8 P22894 1/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
THRB P10828 1/20 0.34
POLB P06746 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALOX15 P16050 1/20 0.33
MAPT P10636 1/20 0.33
HIF1A Q16665 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL954289 0.85 MMP8 (0.43) PKMKDM4ECYP4F2CYP4A11MMP8
SCHEMBL13539346 0.84 MMP8 (0.36) PKMKDM4ECYP4F2CYP4A11MMP8
SCHEMBL1682735 0.81 CYP4F2 (0.41) PKMKDM4ECYP4F2CYP4A11MMP8
SCHEMBL688771 0.78 ALOX15 (0.39) PKMKDM4ECYP4F2CYP4A11MMP8
SCHEMBL13936374 0.78 ALDH1A1 (0.37) PKMKDM4ECYP4F2CYP4A11MMP8
SCHEMBL29088565 0.77 MMP8 (0.38) PKMKDM4ECYP4F2CYP4A11MMP8
SCHEMBL10017426 0.77 PKM (0.37) PKMKDM4ECYP4F2CYP4A11MMP8
SCHEMBL14504422 0.77 MMP8 (0.43) PKMKDM4ECYP4F2CYP4A11MMP8
SCHEMBL13250660 0.76 MMP8 (0.37) PKMKDM4ECYP4F2CYP4A11MMP8
SCHEMBL28502182 0.75 MMP8 (0.42) PKMKDM4ECYP4F2CYP4A11MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0592669-B1 OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 1998-01-28 EP disclosed
US-5665270-A Optically active trifluorolactic acid derivative and liquid crystal composition CHISSO CORPORATION (JP) 1997-09-09 US disclosed
EP-0592669-A1 OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1994-04-20 EP disclosed