Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602954 | 0.95 | SMN1; SMN2 (0.37) | HPGDGPR35SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8602507 | 0.80 | TDP1 (0.34) | HPGDSMN1; SMN2GAAMEN1ALDH1A1 | |
| SCHEMBL7795442 | 0.80 | GAA (0.36) | HPGDSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL8603141 | 0.79 | CA1 (0.36) | HPGDSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8604182 | 0.78 | PPOX (0.32) | HPGDSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8603097 | 0.77 | — | — | |
| SCHEMBL8600582 | 0.76 | POLB (0.34) | MEN1KMT2A | |
| SCHEMBL8603218 | 0.76 | MAPT (0.32) | HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8598803 | 0.76 | ALDH1A1 (0.39) | HPGDSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL8601391 | 0.75 | MAPT (0.39) | HPGDSMN1; SMN2NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |