Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601390 | 0.95 | CYP19A1 (0.36) | PPOXSCN9AHPGDLMNAMAPT | |
| SCHEMBL8603149 | 0.84 | MAPT (0.41) | PPOXHPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL8599215 | 0.83 | ALDH1A1 (0.38) | HPGDLMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL8599849 | 0.82 | LMNA (0.33) | HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL8603214 | 0.80 | LMNA (0.38) | LMNASMN1; SMN2KDM4EALDH1A1NPSR1 | |
| SCHEMBL8599272 | 0.80 | APP (0.39) | HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL8599210 | 0.80 | — | — | |
| SCHEMBL8599212 | 0.78 | HPGD (0.33) | HPGDSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8350503 | 0.77 | ESR1 (0.39) | HPGDLMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL8598792 | 0.77 | PPOX (0.48) | PPOXSCN9AHPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |