Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598803 | 0.89 | ALDH1A1 (0.39) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL8602507 | 0.84 | TDP1 (0.34) | MAPTSMN1; SMN2GAAALDH1A1L3MBTL1 | |
| SCHEMBL8602954 | 0.80 | SMN1; SMN2 (0.37) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL8603212 | 0.79 | SCN9A (0.39) | NAAANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8603429 | 0.76 | PPOX (0.47) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL8601390 | 0.75 | CYP19A1 (0.36) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL8599212 | 0.75 | HPGD (0.33) | NPC1RAB9ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL10410242 | 0.74 | NPC1 (0.43) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL8602564 | 0.71 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2GAAHPGD | |
| SCHEMBL8599203 | 0.70 | ALDH1A1 (0.43) | MAPTSMN1; SMN2GAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |