Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604553 | 0.85 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8604561 | 0.72 | ALDH1A1 (0.44) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL8603621 | 0.70 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8602015 | 0.67 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8603459 | 0.67 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL18065719 | 0.67 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL7228204 | 0.67 | PGR (0.51) | MEN1KMT2AMMP8MMP12MMP13 | |
| SCHEMBL8601740 | 0.65 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8603718 | 0.65 | ALDH1A1 (0.47) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL18065675 | 0.65 | MEN1 (0.56) | NPC1RAB9APTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |