Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599108 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDKMT2AMEN1PKM | |
| SCHEMBL8565008 | 0.79 | HPGD (0.54) | HPGDKMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL8601107 | 0.78 | NAAA (0.45) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8597405 | 0.77 | KDM4E (0.38) | SMN1; SMN2HPGDKMT2AMEN1MAPT | |
| SCHEMBL8597731 | 0.76 | MAPT (0.47) | SMN1; SMN2HPGDKMT2AMEN1PKM | |
| SCHEMBL8599698 | 0.76 | KMT2A (0.43) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8598112 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDKMT2AMEN1PKM | |
| SCHEMBL8562662 | 0.74 | KDM4E (0.39) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8565282 | 0.74 | KDM4E (0.42) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8561746 | 0.73 | PDE3B (0.40) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |