Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598112 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDPOLBCYP1A2MEN1 | |
| SCHEMBL8599362 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDCYP1A2MEN1KMT2A | |
| SCHEMBL8568952 | 0.79 | HTT (0.52) | HPGDCYP1A2MEN1KMT2AMAPT | |
| SCHEMBL8598538 | 0.78 | NAAA (0.45) | SMN1; SMN2HPGDPOLBALDH1A1ALOX15 | |
| SCHEMBL8598526 | 0.77 | HTT (0.38) | SMN1; SMN2HPGDPOLBMEN1KMT2A | |
| SCHEMBL8603232 | 0.76 | GSK3A (0.45) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8567191 | 0.76 | NAPRT (0.50) | SMN1; SMN2CYP1A2MEN1KMT2APKM | |
| SCHEMBL8603015 | 0.75 | ATG4B (0.43) | SMN1; SMN2HPGDPOLBCYP1A2MEN1 | |
| SCHEMBL8563215 | 0.74 | KMT2A (0.42) | SMN1; SMN2POLBMEN1KMT2AMAPT | |
| SCHEMBL8600033 | 0.74 | HPGD (0.50) | SMN1; SMN2HPGDPOLBCYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |