SCHEMBL8626136

SCHEMBL8626136

CCCCCOS(=O)(=O)c1nccc(N)c1[N+](=O)[O-]

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.38
MAPT P10636 3/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
CA1 P00915 9/20 0.36
CA2 P00918 9/20 0.36
CA9 Q16790 8/20 0.36
TXNRD1 Q16881 2/20 0.35
CA12 O43570 3/20 0.35
CA7 P43166 3/20 0.35
CA14 Q9ULX7 3/20 0.35
CA3 P07451 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CA5A P35218 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
NCOA1 Q15788 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.34
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8629459 0.81 CYP19A1 (0.39) CYP19A1MAPTCA1CA2CA9
SCHEMBL8596381 0.81 TXNRD1 (0.49) CYP19A1MAPTTXNRD1GAASMN1; SMN2
SCHEMBL8599555 0.79 CNR1 (0.42) CYP19A1MAPTNPC1RAB9ANCOA1
SCHEMBL8597463 0.78 HTT (0.39) CYP19A1MAPTCA1CA2CA9
SCHEMBL8627058 0.78 CA12 (0.35) MAPTCA1CA2CA9CA12
SCHEMBL8626897 0.78 PAX8 (0.50) CYP19A1NPC1RAB9ATXNRD1SMN1; SMN2
SCHEMBL8628083 0.77 CYP19A1 (0.37) CYP19A1MAPTNPC1RAB9ACA1
SCHEMBL8566243 0.77 MGMT (0.46) CYP19A1MAPTNPC1RAB9ACA1
SCHEMBL8626079 0.75 CA2 (0.37) CYP19A1MAPTNPC1RAB9ACA1
SCHEMBL8629877 0.74 LMNA (0.38) MAPTCA2TXNRD1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735025-B1 Process for producing aminonitropyridines SUMITOMO CHEMICAL CO (JP) 1998-07-01 EP disclosed
US-5648496-A AMINATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-15 US disclosed
EP-0735025-A1 Process for producing aminonitropyridines SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed