⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20464448 | 0.85 | ALDH1A1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL6231685 | 0.82 | ALDH1A1 (0.40) | — | |
| SCHEMBL21945129 | 0.80 | KCNH2 (0.37) | — | |
| SCHEMBL4324417 | 0.80 | — | — | |
| SCHEMBL24618609 | 0.77 | KCNH2 (0.38) | — | |
| SCHEMBL18644049 | 0.77 | RAB9A (0.36) | — | |
| SCHEMBL10154714 | 0.77 | KCNH2 (0.38) | — | |
| SCHEMBL22912519 | 0.77 | ALDH1A1 (0.37) | — | |
| SCHEMBL294058 | 0.77 | KCNH2 (0.35) | — | |
| SCHEMBL16373730 | 0.77 | RAB9A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1413286-A1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | L'OREAL (FR) | 2004-04-28 | — | — | EP | claimed |
| EP-4739694-A2 | MACROCYCLIC COMPOUNDS AND USE AS TYK2 INHIBITORS | Blossomhill Therapeutics, Inc. (US) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025010294-A2 | MACROCYCLIC COMPOUNDS AND USE AS TYK2 INHIBITORS | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2025-01-09 | — | — | WO | disclosed |
| CN-117915919-A | Polymorphs, pharmaceutical compositions and uses of azaaromatic ring compounds and pharmaceutically acceptable salts thereof | 上海海雁医药科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-20230145793-A1 | SUBSTITUTED PYRIMIDINE OR PYRIDINE AMINE DERIVATIVE, COMPOSITION THEREOF, AND MEDICAL USE THEREOF | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-05-11 | — | — | US | disclosed |
| US-20230145793-A1 | SUBSTITUTED PYRIMIDINE OR PYRIDINE AMINE DERIVATIVE, COMPOSITION THEREOF, AND MEDICAL USE THEREOF | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-05-11 | — | — | US | disclosed |
| EP-4122927-A1 | SUBSTITUTED PYRIMIDINE OR PYRIDINE AMINE DERIVATIVE, COMPOSITION THEREOF, AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. (CN) | 2023-01-25 | — | — | EP | disclosed |
| US-20220220117-A1 | 9-SUBSTITUTED AMINO TRIAZOLO QUINAZOLINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | MERCK SHARP & DOHME CORP. (US) | 2022-07-14 | — | — | US | disclosed |
| US-11312719-B2 | 9-substituted amino triazolo quinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and their use | MERCK SHARP & DOHME CORP. (US) | 2022-04-26 | — | — | US | disclosed |
| US-20210355104-A1 | ADENOSINE RECEPTOR BINDING COMPOUNDS | NIKANG THERAPEUTICS, INC. (US) | 2021-11-18 | — | — | US | disclosed |
| EP-0998258-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | L'OREAL (FR) | 2000-05-10 | — | — | EP | disclosed |
| EP-0998257-A1 | OXIDISING COMPOSITION AND USES FOR TREATING KERATIN FIBRES | L'OREAL (FR) | 2000-05-10 | — | — | EP | disclosed |
| EP-0975317-A1 | OXIDISING COMPOSITION AND USE FOR DYEING, PERMANENTLY SETTING OR BLEACHING KERATIN FIBRES | L'OREAL (FR) | 2000-02-02 | — | — | EP | disclosed |
| EP-0975318-A1 | OXIDISING COMPOSITION AND USES FOR DYEING, PERMANENTLY SETTING OR BLEACHING KERATIN FIBRES | L'OREAL (FR) | 2000-02-02 | — | — | EP | disclosed |
| EP-0966247-A1 | OXIDISING COMPOSITION AND USES FOR DYEING, PERMANENTLY SETTING OR BLEACHING KERATIN FIBRES | L'OREAL (FR) | 1999-12-29 | — | — | EP | disclosed |
| WO-1999017721-A1 | OXIDISING COMPOSITION AND USES FOR DYEING, PERMANENTLY SETTING OR BLEACHING KERATIN FIBRES | L'OREAL (FR) | 1999-04-15 | — | — | WO | disclosed |
| WO-1999017723-A1 | OXIDISING COMPOSITION AND USE FOR DYEING, PERMANENTLY SETTING OR BLEACHING KERATIN FIBRES | L'OREAL (FR) | 1999-04-15 | — | — | WO | disclosed |
| WO-1999017728-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | L'OREAL (FR) | 1999-04-15 | — | — | WO | disclosed |
| WO-1999017727-A1 | OXIDISING COMPOSITION AND USES FOR DYEING, PERMANENTLY SETTING OR BLEACHING KERATIN FIBRES | L'OREAL (FR) | 1999-04-15 | — | — | WO | disclosed |
| WO-1999017724-A1 | OXIDISING COMPOSITION AND USES FOR TREATING KERATIN FIBRES | L'OREAL (FR) | 1999-04-15 | — | — | WO | disclosed |