Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | WNT3A | P56704 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504833 | 0.93 | CES2 (0.59) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| SCHEMBL29601127 | 0.93 | CES2 (0.59) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| Bromide SCHEMBL1016601 | 0.91 | CES2 (0.57) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| Hydrochloric Acid SCHEMBL6833226 | 0.91 | CES2 (0.57) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| Bromide SCHEMBL29601697 | 0.91 | CES2 (0.57) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| Bromide SCHEMBL5121089 | 0.89 | CES2 (0.55) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| Pyridine SCHEMBL8602271 | 0.86 | LMNA (0.55) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| Pyridine SCHEMBL18321129 | 0.79 | GSK3B (0.76) | L3MBTL1LMNACES1CTNNB1KMT2A | |
| 2-Picolinic Acid SCHEMBL4813302 | 0.79 | LMNA (0.87) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL28365061 | 0.79 | LMNA (0.87) | L3MBTL1LMNANAPRTP4HTMCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817774-A | Unsymmetrical complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | STERLING WINTHROP INCORPORATION (US) | 1998-10-06 | — | — | US | disclosed |