SCHEMBL504833

SCHEMBL504833

O=C(CBr)c1ccccn1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
L3MBTL1 Q9Y468 4/20 0.57
GRM4 Q14833 1/20 0.57
LMNA P02545 1/20 0.57
NAPRT Q6XQN6 1/20 0.57
P4HTM Q9NXG6 1/20 0.57
ALDH1A1 P00352 2/20 0.55
GSK3B P49841 2/20 0.55
CTNNB1 P35222 5/20 0.53
WNT3A P56704 4/20 0.53
KMT2A Q03164 2/20 0.52
PTPN1 P18031 1/20 0.48
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
TLR7 Q9NYK1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601127 1.00 CES2 (0.59) CES2CES1L3MBTL1GRM4LMNA
Bromide SCHEMBL29601697 0.98 CES2 (0.57) CES2CES1L3MBTL1GRM4LMNA
Hydrochloric Acid SCHEMBL6833226 0.98 CES2 (0.57) CES2CES1L3MBTL1GRM4LMNA
Bromide SCHEMBL1016601 0.98 CES2 (0.57) CES2CES1L3MBTL1GRM4LMNA
Bromide SCHEMBL5121089 0.96 CES2 (0.55) CES2CES1L3MBTL1GRM4LMNA
Pyridine SCHEMBL8599632 0.93 L3MBTL1 (0.55) CES2CES1L3MBTL1GRM4LMNA
SCHEMBL12777709 0.83 CES2 (0.59) CES2CES1L3MBTL1GRM4LMNA
SCHEMBL2470002 0.83 CTNNB1 (0.71) CES2CES1L3MBTL1GRM4LMNA
SCHEMBL253276 0.83 CES2 (0.64) CES2CES1L3MBTL1GRM4LMNA
SCHEMBL29355245 0.83 CES2 (0.64) CES2CES1L3MBTL1GRM4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 533 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58110505-A None JP disclosed
US-20250388582-A1 NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF ILDONG PHARMACEUTICAL CO LTD (KR) 2025-12-25 US disclosed
EP-4626896-A1 POLYELECTROPHILIC METALATED HETEROCYCLES DERIVED FROM 2-(PYRIDIN-2-YL)IMIDAZO[1,2-A]PYRIDINE AND USE THEREOF AS CHEMOTHERAPEUTIC AGENTS Universidad del País Vasco/Euskal Herriko Unibertsitatea (ES) 2025-10-08 EP disclosed
EP-4556476-A1 NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF Ildong Pharmaceutical Co., Ltd. (KR) 2025-05-21 EP disclosed
WO-2025015429-A1 IMIDAZOPYRIMIDINE-BASED MULTIMETALLIC CATALYSTS SCHIPPER DEREK JAMES (CA) 2025-01-23 WO disclosed
EP-3800186-B1 CYANOPYRROLIDINES AS DUB INHIBITORS FOR THE TREATMENT OF CANCER MISSION THERAPEUTICS LTD (GB) 2024-10-02 EP disclosed
CN-118176185-A 2- (Aryl-2-yl) morpholine and deuterated derivative thereof, preparation method and application 上海翰森生物医药科技有限公司 2024-06-11 CN disclosed
WO-2024115550-A1 POLYELECTROPHILIC METALATED HETEROCYCLES DERIVED FROM 2-(PYRIDIN-2-YL)IMIDAZO[1,2-A]PYRIDINE AND USE THEREOF AS CHEMOTHERAPEUTIC AGENTS UNIVERSIDAD DEL PAÍS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (ES) 2024-06-06 WO disclosed
EP-4355426-A1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE COMPOUNDS AS CDK INHIBITORS AND THEIR THERAPEUTIC USE Carrick Therapeutics Limited (IE) 2024-04-24 EP disclosed
US-20240109914-A1 IMIDAZOTHIAZOLE COMPOUNDS AND ANALOGS THEREOF AND METHODS FOR TREATING NEMATODE INFECTIONS IN PLANTS THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2024-04-04 US disclosed
EP-0306300-A2 Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors SMITHKLINE BEECHAM CORPORATION (US) 1989-03-08 EP disclosed
US-4692525-A HYPOTENSIVE AGENTS, ESTERIFICATION MALESCI S.P.A. ISTITUTO FARMACOBIOLOGICO (IT) 1987-09-08 US disclosed
EP-0190900-A2 Cephalosporin compounds, their production, and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-08-13 EP disclosed
US-4578467-A Process for the preparation of 1-pyridyl-alkyl-4-aryl piperazines which are useful as antihypertensive compounds, their separation into the respective optical antipodes, and the stereoisomeric compounds so obtained MALESCI S.P.A. INSTITUTO FARMACOBIOLOGICO (IT) 1986-03-25 US disclosed
EP-0129409-A2 Thiazolo - and thiazinobenzimidazoles JOHN WYETH & BROTHER LIMITED (GB) 1984-12-27 EP disclosed
EP-0092459-A2 Imidazo(1,2-a)pyridines, their preparation and therapeutical use SYNTHELABO (FR) 1983-10-26 EP disclosed
JP-S58110505-A GERMICIDE ISHIHARA SANGYO KAISHA LTD 1983-07-01 JP disclosed
EP-0072743-A1 1,2-Dithiol-3-ylidene ammonium derivatives, process for their preparation and medicines containing them RHONE-POULENC SANTE (FR) 1983-02-23 EP disclosed
US-4254267-A HYPOTENSIVE ACTIVITY E. R. SQUIBB & SONS, INC. (US) 1981-03-03 US disclosed
US-4005212-A ANTIDEPRESSANT, ANOREXIGENIC, PSYCHOENERGIZING, 2-PHENYL-2,3,5,6-TETRAHYDROIMIDAZO(2,1-B)THIAZOLE RHONE-POULENC S.A. (FR) 1977-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109914-A1 IMIDAZOTHIAZOLE COMPOUNDS AND ANALOGS THEREOF AND METHODS FOR TREATING NEMATODE INFECTIONS IN PLANTS NISCH, ABAT, ICMT CES2 2538/4885CES1 1880/4885L3MBTL1 687/4885
US-20250388582-A1 NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF GBA1, PIKFYVE, MAN2B1 CES2 1314/4885CES1 108/4885L3MBTL1 816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.