Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754770 | 0.81 | GAA (0.31) | GAAL3MBTL1 | |
| SCHEMBL475361 | 0.81 | APLNR (0.38) | GAAL3MBTL1 | |
| SCHEMBL8599636 | 0.79 | GAA (0.48) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL51127 | 0.79 | KMT2A (0.31) | GAAL3MBTL1 | |
| SCHEMBL5491826 | 0.78 | APLNR (0.35) | — | |
| SCHEMBL932260 | 0.76 | ADAM17 (0.30) | — | |
| SCHEMBL1433982 | 0.76 | ATM (0.33) | GAAL3MBTL1 | |
| SCHEMBL3057229 | 0.76 | SLC18A2 (0.30) | — | |
| SCHEMBL8676534 | 0.73 | GAA (0.31) | GAAL3MBTL1 | |
| SCHEMBL7936712 | 0.72 | MAPT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822835-A1 | HYBRID MAGNETIC RESONANCE CONTRAST AGENTS | IMARX PHARMACEUTICAL CORP. (US) | 1998-02-11 | — | — | EP | claimed |
| WO-1996032967-A1 | HYBRID MAGNETIC RESONANCE CONTRAST AGENTS | IMARX PHARMACEUTICAL CORPORATION (US) | 1996-10-24 | — | — | WO | claimed |
| US-5407657-A | Containing a metal chelate and a free radical nitroxide | IMARX THERAPEUTICS, INC. | 1995-04-18 | — | — | US | claimed |
| US-5407657-A | Containing a metal chelate and a free radical nitroxide | IMARX THERAPEUTICS, INC. | 1995-04-18 | — | — | US | disclosed |