SCHEMBL475361

SCHEMBL475361

CC1(C)CC(C(=O)O)C(C)(C)N1[O]

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.38
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
GRM4 Q14833 4/20 0.31
CYP2C19 P33261 3/20 0.31
ALDH1A1 P00352 2/20 0.31
CYP1A2 P05177 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
GRM8 O00222 1/20 0.31
GRM6 O15303 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALOX15 P16050 1/20 0.31
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5491826 0.96 APLNR (0.35) APLNRSLC1A2SLC1A1GRM4CYP2C19
SCHEMBL9754770 0.83 GAA (0.31) GAAL3MBTL1
SCHEMBL8599635 0.81 CHRNB2 (0.32) GAAL3MBTL1
SCHEMBL51127 0.81 KMT2A (0.31) KMT2AGAAL3MBTL1
SCHEMBL438903 0.79 SLC1A2 (0.42) APLNRSLC1A2SLC1A1ALDH1A1L3MBTL1
SCHEMBL13225976 0.78 GAA (0.50) APLNRSLC1A2SLC1A1GRM4CYP2C19
SCHEMBL4397787 0.78 GAA (0.50) APLNRSLC1A2SLC1A1GRM4CYP2C19
SCHEMBL697858 0.78 GAA (0.50) APLNRSLC1A2SLC1A1GRM4CYP2C19
SCHEMBL7634478 0.78 APLNR (0.38) APLNRSLC1A2SLC1A1GRM4CYP2C19
SCHEMBL1433982 0.78 ATM (0.33) CYP2C19CYP1A2MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4714957-A1 (METH)ACRYLATE COMPOUND PRODUCTION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-03-25 EP claimed
EP-4100010-B1 NITROXIDE COMPOUNDS FOR USE IN THE TREATMENT OF OPIOID-INDUCED RESPIRATORY DEPRESSION (OIRD) UNIV CASE WESTERN RESERVE (US) 2026-01-07 EP claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
EP-4599224-A1 RAPID GELLING AQUEOUS MOUNTING MEDIA Life Technologies Corporation (US) 2025-08-13 EP claimed
EP-3682222-B1 REFRACTIVE INDEX MATCHING FORMULATIONS LIFE TECHNOLOGIES CORP (US) 2025-05-07 EP claimed
US-20250041285-A1 MODIFYING THE EXPRESSION LEVEL OF A GENE ENCODING AN CYCLOOXYGENASE ENZYME BY TREATING A HUMAN SUBJECT WITH A NITROXIDE HABASH LOUIS (US) 2025-02-06 US claimed
US-12208089-B2 Adjusting expression level of a gene encoding a Sirtuin protein by treating a human subject with a nitroxide HABASH LOUIS (US) 2025-01-28 US claimed
US-20240415826-A1 MODULATING EXPRESSION LEVEL OF A GENE ENCODING AN UNCOUPLING PROTEIN BY TREATING A HUMAN SUBJECT WITH A NITROXIDE HABASH LOUIS (US) 2024-12-19 US claimed
WO-2024237180-A1 (METH)ACRYLATE COMPOUND PRODUCTION METHOD 三菱瓦斯化学株式会社 2024-11-21 WO claimed
US-20240272049-A1 REFRACTIVE INDEX MATCHING FORMULATIONS LIFE TECHNOLOGIES CORP (US) 2024-08-15 US claimed
US-5714510-A Topical proxyl composition and method PROCTOR PETER H (US) 1998-02-03 US claimed
EP-0691329-B1 Process for the preparation of polyencarbonyl compounds with high content of the all E-isomer and their acetals or ketales BASF AG (DE) 1997-10-29 EP claimed
EP-0797600-A1 HIGH MOLECULAR WEIGHT POLYSTYRENE PRODUCTION BY VINYLACID CATALYZED FREE RADICAL POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1997-10-01 EP claimed
WO-1996018663-A1 HIGH MOLECULAR WEIGHT POLYSTYRENE PRODUCTION BY VINYLACID CATALYZED FREE RADICAL POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1996-06-20 WO claimed
EP-0691329-A1 Process for the preparation of polyencarbonyl compounds with high content of the all E-isomer and their acetals or ketales BASF AKTIENGESELLSCHAFT (DE) 1996-01-10 EP claimed
EP-0327263-B1 Hair growth stimulation with nitroxide and other radicals PROCTOR PETER H (US) 1994-09-07 EP claimed
US-4925652-A NUCLEAR MAGNETIC RESONANCE SCHERING AKTIENGESELLSCHAFT (DE) 1990-05-15 US claimed
EP-0133674-B1 NITROXYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND DIAGNOSTIC AGENTS CONTAINING THEM SCHERING AKTIENGESELLSCHAFT (DE) 1989-09-20 EP claimed
US-4845090-A NUCLEAR MAGNETIC RESONANCE SCHERING AKTIENGESELLSCHAFT (DE) 1989-07-04 US claimed
WO-1988005653-A1 TOPICAL COMPOSITION FOR STIMULATING HAIR GROWTH WITH STABLE FREE RADICALS PROCTOR PETER H (US) 1988-08-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041285-A1 MODIFYING THE EXPRESSION LEVEL OF A GENE ENCODING AN CYCLOOXYGENASE ENZYME BY TREATING A HUMAN SUBJECT WITH A NITROXIDE HMOX2, QSOX1, GPX1 APLNR 2550/4885SLC1A2 1502/4885SLC1A1 1461/4885
US-12208089-B2 Adjusting expression level of a gene encoding a Sirtuin protein by treating a human subject with a nitroxide SIRT2, SIRT6, TXNRD2 APLNR 2480/4885SLC1A2 2047/4885SLC1A1 2743/4885
US-20240415826-A1 MODULATING EXPRESSION LEVEL OF A GENE ENCODING AN UNCOUPLING PROTEIN BY TREATING A HUMAN SUBJECT WITH A NITROXIDE TXNRD2, TXN2, TXNRD1 APLNR 1889/4885SLC1A2 686/4885SLC1A1 1107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.