Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10332242 | 0.82 | POLB (0.44) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8565327 | 0.80 | MEN1 (0.52) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8601694 | 0.77 | ALDH1A1 (0.42) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8603033 | 0.77 | CYP1A2 (0.47) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8597358 | 0.74 | DHFR (0.41) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8600860 | 0.74 | DHFR (0.41) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8598975 | 0.74 | POLB (0.41) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL5452427 | 0.74 | MAPT (0.48) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8597485 | 0.74 | DHFR (0.45) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8598588 | 0.73 | POLB (0.40) | POLBKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |