Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MGMT | P16455 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597358 | 0.82 | DHFR (0.41) | DHFRLMNAL3MBTL1MAPTCYP1A2 | |
| SCHEMBL8560428 | 0.82 | MEN1 (0.47) | LMNAL3MBTL1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL8601762 | 0.80 | TDP1 (0.43) | DHFRLMNAL3MBTL1MAPTCYP1A2 | |
| SCHEMBL8597355 | 0.78 | TLR8 (0.44) | LMNAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8599452 | 0.78 | MAPT (0.43) | LMNAMAPTSMN1; SMN2CYP3A4MGMT | |
| SCHEMBL11128635 | 0.76 | MEN1 (0.50) | LMNAL3MBTL1MAPTCYP1A2CYP2C9 | |
| SCHEMBL8596169 | 0.75 | MAPT (0.41) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8600230 | 0.75 | GSK3A (0.48) | LMNAMAPTSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL8567950 | 0.75 | CYP3A4 (0.47) | LMNAMAPTSMN1; SMN2CYP3A4RAB9A | |
| SCHEMBL8599760 | 0.74 | POLB (0.41) | DHFRLMNAL3MBTL1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |