Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967634 | 0.88 | HTR1A (0.51) | SIGMAR1DRD2HTR1ADRD3HTR2A | |
| SCHEMBL8600561 | 0.88 | MAPT (0.47) | SIGMAR1KCNH2DRD2HTR1ADRD3 | |
| SCHEMBL7957292 | 0.79 | SIGMAR1 (0.52) | SIGMAR1KCNH2CYP2D6DRD2HTR1A | |
| SCHEMBL5988317 | 0.73 | KCNH2 (0.88) | SIGMAR1KCNH2CYP2D6DRD2HTR1A | |
| SCHEMBL7718541 | 0.73 | SIGMAR1 (1.00) | SIGMAR1KCNH2CYP2D6DRD2HTR1A | |
| SCHEMBL4528457 | 0.72 | KCNH2 (1.00) | SIGMAR1KCNH2CYP2D6DRD2HTR1A | |
| SCHEMBL11762555 | 0.70 | KCNH2 (0.69) | SIGMAR1KCNH2CYP2D6DRD2HTR1A | |
| SCHEMBL9041083 | 0.70 | KCNH2 (0.80) | SIGMAR1KCNH2CYP2D6DRD2HTR1A | |
| SCHEMBL15961278 | 0.70 | SIGMAR1 (0.79) | SIGMAR1KCNH2DRD2HTR1AHTR2A | |
| SCHEMBL11563433 | 0.70 | SIGMAR1 (0.79) | SIGMAR1KCNH2CYP2D6DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |