Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967634 | 0.88 | HTR1A (0.51) | HRH1L3MBTL3L3MBTL1SIGMAR1DRD2 | |
| SCHEMBL8599796 | 0.88 | SIGMAR1 (0.56) | HRH1SIGMAR1KCNH2DRD2DRD4 | |
| SCHEMBL7949455 | 0.80 | MAPK1 (0.46) | MAPTNPSR1HRH1L3MBTL3L3MBTL1 | |
| SCHEMBL15961278 | 0.71 | SIGMAR1 (0.79) | MAPTNPSR1MEN1KMT2ASIGMAR1 | |
| SCHEMBL15961331 | 0.71 | MAPT (0.83) | MAPTNPSR1MEN1KMT2ASIGMAR1 | |
| SCHEMBL7961393 | 0.71 | DRD4 (0.58) | MAPTNPSR1HRH1L3MBTL3L3MBTL1 | |
| SCHEMBL7957403 | 0.70 | MAPT (0.46) | MAPTNPSR1HRH1L3MBTL3L3MBTL1 | |
| SCHEMBL7963946 | 0.70 | MAPT (0.46) | MAPTNPSR1HRH1L3MBTL3L3MBTL1 | |
| SCHEMBL13321082 | 0.70 | KDM4E (0.71) | MAPTNPSR1KDM4ESIGMAR1KCNH2 | |
| SCHEMBL10995656 | 0.70 | MAPT (0.58) | MAPTNPSR1HRH1ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |