Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686428 | 0.86 | OPRL1 (0.39) | GAAATML3MBTL1RECQLPOLB | |
| SCHEMBL8689003 | 0.81 | MEN1 (0.38) | RECQLKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8599859 | 0.76 | MARS1 (0.39) | ATML3MBTL1KMT2AALDH1A1MEN1 | |
| SCHEMBL11205040 | 0.73 | KMT2A (0.65) | GAAATML3MBTL1RECQLPOLB | |
| SCHEMBL8977289 | 0.73 | NPSR1 (0.46) | GAAATML3MBTL1KMT2AMAPT | |
| SCHEMBL8601018 | 0.72 | MAPT (0.45) | GAAL3MBTL1POLBKMT2AMAPT | |
| SCHEMBL8603507 | 0.72 | RPS6KA5 (0.35) | — | |
| SCHEMBL2161149 | 0.71 | HTT (0.42) | GAAL3MBTL1POLBKMT2AMAPT | |
| SCHEMBL8184305 | 0.70 | ALDH1A1 (0.50) | GAAATML3MBTL1RECQLPOLB | |
| SCHEMBL7896709 | 0.70 | BCAT2 (0.48) | GAAATML3MBTL1RECQLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767286-A | REACTING A TETRAZOLINONE WITH A CARBAMOYL CHLORIDE IN THE PRESENCE OF 4-DIMETHYLAMINOPYRIDINE | NIHON BAYER AGROCHEM K. K. (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0646577-B1 | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1998-06-03 | — | — | EP | disclosed |
| US-5710278-A | Herbicidal 1-pyridyltetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1998-01-20 | — | — | US | disclosed |
| US-5641727-A | Herbicidal 1-pyridyltetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0643049-B1 | A process for the preparation of 1-substituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1997-05-14 | — | — | EP | disclosed |
| US-5502204-A | REACTING WITH ETHYLENE OXIDE DERIVATIVE | NIHON BAYER AGROCHEM K.K. (JP) | 1996-03-26 | — | — | US | disclosed |
| EP-0692482-A2 | 1-pyridyltetrazolinone derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1996-01-17 | — | — | EP | disclosed |
| EP-0646577-A1 | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1995-04-05 | — | — | EP | disclosed |
| EP-0643049-A1 | A process for the preparation of 1-substituted-5(4H)-tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1995-03-15 | — | — | EP | disclosed |